The role of CBD oil in managing neuropathic pain

29 May 2023


Neuropathic pain, a complex, chronic pain state, is generally accompanied by tissue injury. With neuropathic pain, the nerve fibers themselves may be damaged, dysfunctional, or injured. These damaged nerve fibers send incorrect signals to other pain centers, leading to a cascade of effects. The impact of a nerve fiber injury includes a change in nerve function both at the site of injury and in areas around the injury. We will explore the role of CBD oil in managing neuropathic pain in this blog post!


Jensen, T. S., Baron, R., Haanpää, M., Kalso, E., Loeser, J. D., Rice, A. S., & Treede, R. D. (2011). A new definition of neuropathic pain. Pain, 152(10), 2204-2205.


Understanding Neuropathic Pain: Causes and Symptoms


Dealing with neuropathic pain can be a real struggle.


Neuropathic pain can result from various conditions, including diabetes, multiple sclerosis, cancer, HIV, physical trauma, and others.


It can also be a side effect of certain medications. Symptoms vary widely, from sensations described as spontaneous pain, burning, tingling, or shooting pain, to more complex symptoms such as the feeling of 'pins and needles,' extreme sensitivity to touch, or a lack of sensation entirely.


The Impact of Neuropathic Pain on Quality of Life


Living with neuropathic pain can significantly impact the quality of life.


The constant or intermittent discomfort can lead to sleep disturbances, emotional distress, and a decrease in physical activity. It can affect a person's ability to work, engage in social activities, and overall enjoyment of life.


The psychological impact can be as debilitating as the physical pain itself, leading to depression, anxiety, and other mental health issues.


Understanding CBD Oil


Our iHeal is one of our recommended CBD oils for pain management.


CBD, or cannabidiol, is one of the many compounds found in the cannabis plant.


Unlike THC, another well-known compound, CBD does not have psychoactive properties, meaning it doesn't cause the 'high' associated with cannabis use.


Mechoulam, R., Parker, L. A., & Gallily, R. (2002). Cannabidiol: an overview of some pharmacological aspects. The Journal of Clinical Pharmacology, 42(S1).


What is CBD Oil? A Brief Overview


CBD oil is a product derived from cannabis. It's a type of cannabinoid, which are the chemicals naturally found in marijuana plants. Even though it comes from marijuana plants, CBD doesn't create a 'high' effect or any form of intoxication — that's caused by another cannabinoid, known as THC.


CBD oil is made by extracting CBD from the cannabis plant, then diluting it with a carrier oil like coconut or hemp seed oil.


The Science Behind CBD: How it Works in the Body


CBD oil works harmoniously with the human body.


CBD works by interacting with the body's endocannabinoid system (ECS), a complex cell-signaling system that plays a role in regulating a range of functions and processes, including sleep, mood, appetite, memory, and pain.


While the body produces its own endocannabinoids, CBD influences the ECS by slowing the breakdown of the body's endocannabinoids or by binding to cannabinoid receptors. 


In essence - when You are giving CBD to Your body, You are giving it the correct fuel to run in the best way. Even further, similar fuel exists in the body already, it just needs some stimulation!


CBD Oil and Neuropathic Pain: The Connection


The relationship between CBD oil and neuropathic pain is a fascinating area of study. The endocannabinoid system, which CBD interacts with, plays a crucial role in the body's pain perception.


The Endocannabinoid System and Pain Perception


The endocannabinoid system (ECS) is a complex cell-signaling system in the body that plays a role in maintaining homeostasis, or balance, in various physiological functions. This includes pain perception.


The ECS is composed of endocannabinoids, receptors, and enzymes. When there is an imbalance in the body, such as inflammation or nerve damage causing neuropathic pain, the ECS kicks in to help restore balance.


How CBD Oil Interacts with the Nervous System


CBD is in "dialogue" with the ECS within the human body.


CBD interacts with the ECS and other components of the nervous system, influencing the perception of pain.


While the exact mechanisms are still under investigation, research suggests that CBD inhibits the absorption of anandamide, a natural cannabinoid molecule that regulates pain.


Mechoulam, R., & Parker, L. A. (2013). The endocannabinoid system and the brain. Annual review of psychology, 64, 21-47.


CBD Oil and Inflammation: A Key Factor in Neuropathic Pain


Inflammation is a common factor in the development of neuropathic pain. Studies suggest that CBD has anti-inflammatory properties.


By reducing inflammation, CBD helps manage neuropathic pain.


Nagarkatti, P., Pandey, R., Rieder, S. A., Hegde, V. L., & Nagarkatti, M. (2009). Cannabinoids as novel anti-inflammatory drugs. Future medicinal chemistry, 1(7), 1333-1349.


Scientific Evidence on CBD Oil for Neuropathic Pain


The scientific community has been actively researching the benefits of CBD oil for neuropathic pain.


Several studies have shown promising results.


For instance, a 2020 review of 16 previously published studies testing the use of CBD for pain relief found that CBD was effective in overall pain management and didn't cause negative side effects.


Mücke, M., Phillips, T., Radbruch, L., Petzke, F., & Häuser, W. (2018). Cannabis-based medicines for chronic neuropathic pain in adults. The Cochrane database of systematic reviews, 3(3), CD012182.


Using CBD Oil for Neuropathic Pain Management


CBD is a new and effective alternative to more traditional methods for neuropathic pain management.


CBD oil has emerged as a potential tool for managing neuropathic pain. Its potential benefits stem from its interaction with the body's endocannabinoid system, which plays a crucial role in pain perception and inflammation.


Different Forms of CBD for Pain Management: Oils, Capsules, Topicals, etc.


If You prefer CBD capsules to CBD oil - our iPill+ is a great option for neuropathic pain relief.


CBD is available in various forms, each with its own advantages and disadvantages.


CBD oil, which can be taken orally or applied topically, is perhaps the most common.


However, CBD is also available in capsules, edibles, and even in topical forms like creams and lotions. 


The choice of form can depend on various factors, including personal preference, desired speed of onset, and the area of the body where the pain is felt.


iCBD Global recommends the following products for neuropathic pain:


iMuscle (a topical cream)

iAnimal (CBD oil)

iHeal (our most potent CBD oil)

iPill+ (capsules)


Dosage and Administration: How Much CBD Oil Should You Take?


iAnimal is one of iCBD Global's best when it comes to managing neuropathic pain.


Determining the right dosage of CBD can be tricky, as it can depend on various factors, including the severity of the pain, the form of CBD being used, and individual factors like body weight and metabolism.


It's generally recommended to start with a low dose and gradually increase until the desired effect is achieved.


iCBD Global recommends 3-5 drops of CBD oil 3 times a day.


Read our blog on dosing here.


Potential Side Effects and Risks of CBD Oil


While CBD is generally well-tolerated, it can cause side effects in some people. These can include dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue.


CBD can also interact with other medications, so it's important to consult with a healthcare provider before starting to use CBD oil.


Read our blog on the safety of CBD oil here.


Comparing CBD Oil with Other Neuropathic Pain Treatments


You can ultimately combine CBD oil with other types of treatments. But it's also a matter of choosing between nature and artificially made remedies that weren't meant to interact with our bodies in a harmonious way.


There are various treatments available for neuropathic pain, ranging from over-the-counter and prescription medications to physical therapy and alternative therapies.


Traditional treatments for neuropathic pain often involve medications like nonsteroidal anti-inflammatory drugs (NSAIDs), anticonvulsants, antidepressants, and opioids.


Physical therapy and cognitive-behavioral therapy can also be part of a comprehensive pain management plan.


CBD Oil vs. Other Treatments: Pros and Cons


Compared to traditional treatments, CBD oil can offer certain advantages, such as a lower risk of side effects and benefits for overall well-being. 


CBD is also a natural alternative to more man-made prescription drugs. Keeping Your body in harmony with nature.


Complementary Approach: Using CBD Oil Alongside Other Treatments


For many people, a combination of treatments may be the most effective approach to managing neuropathic pain.


CBD oil can be used alongside other treatments, but it's important to discuss this with a healthcare provider to avoid any potential interactions or adverse effects.


Testimonials Using CBD Oil for Neuropathic Pain


Here at iCBD global, we witness truly exciting healing stories almost daily. We are thrilled to share these with You to ease any concerns You still might have giving CBD oil a chance.


You can check out iAnimal here - one of our best!


CBD often can and does change lives! We feel privileged to be a part of this!


Team iCBD Global


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